All lab markers

Thyroid

TPO Antibodies

The primary Hashimoto's antibody — an attack on the enzyme the thyroid uses to make hormone. Higher results are the ones to watch.

What commonly moves it

  • Thyroid autoimmunityAntibody-driven gland damage shifts TSH and free hormone levels.
  • Estrogen decline / HRT gapFalling estrogen can unmask thyroid autoimmunity and shift lipids.
  • Absorption problemGut permeability or low stomach acid limits iron, B12 and fat-soluble uptake.

What it can affect downstream

TSHFree T4

These are commonly described physiological relationships, shared for education. They are not a diagnosis and cannot account for your medications, history, or symptoms — discuss your results with a licensed clinician.

Watching TPO Antibodies over time?

Dose Compass charts each draw, flags meaningful moves, and helps you prepare questions for your clinician.

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